What are the Effects of MDMA on PTSD Patients?

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MDMA shows promise in treatment of PTSD, U.S. psychiatrist says

Post-Traumatic Stress Disorder (PTSD) is a chronic and often a highly destructive illness that greatly affects the quality of life of the person who has PTSD and is associated with high rates of suicide and psychological disability.

Currently, it is a global public mental health problem with more than 20 million people suffering from this condition in the United States alone.

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PTSD has various causes, including war, torture, accidents, sexual assault, child abuse, natural calamities and other extreme stress events.

There have been a variety of treatment options for this condition, some more controversial than others.

One of the more recent, but unusual treatment option is MDMA-assisted psychotherapy. MDMA is short for 3, 4 methylenedioxymethamphetamine.

It is an ingredient found in the street drugs referred to as ecstasy or molly.

Studies conducted in recent years add to the body of positive evidence that this psychoactive and psychedelic drug derived from safrole oil could help PTSD patients.

It is important to note that the drug itself is not the therapy, but a tool used by both the clinicians and PTSD victims.


One of the major studies on MDMA and its impact on PTSD patients was carried out by the Multidisciplinary Association for Psychedelic Studies (MAPS) in Canada, Israel, The United States and Switzerland.

The studies were approved by the respective drug boards of the involved countries including the FDA.

While the results were not convincing for all the patients in the study, MDMA did prove useful for the treatment of some of the most affected patients.

MDMA was in this case used to break down most of the barriers associated with PTSD therapy treatments.

Therefore, as mentioned before its use is rather complementary.

The researchers applauded MDMA for its ability to significantly quicken the results achieved through conventional therapy techniques.

The patients were given an equivalent of a street dose of MDMA spaced out over several weeks.

This was complemented with hours of non-medicated talk therapy carried out by professional mental-health clinicians.

According to the results MDMA has the ability to enhance communication skills, promote deep self-analysis, break down emotional barriers and act as a catalyst to psychotherapy.

A significant percentage of the patients in the trials recorded notable improvement after a short period of MDMA-assisted psychotherapy.

MDMA’s effect on PTSD patients is attributed to the chemical reactions in causes in the body.

MDMA is known to prevent activities in the left amygdala, the part of the brain associated with anxiety, fear, and mental trauma.

This may improve interpersonal trust between the patients and the therapists thus facilitating psychotherapy sessions.

It also triggers the release of serotonin, dopamine, and oxytocin. Serotonin is the neurotransmitter that helps in the regulation of one’s moods.

Dopamine regulates emotional response while oxytocin results in improved bonding, intimacy, and trust.

The compounded action of these three substances enables PTSD patients to process and gradually overcome the psychological trauma.

The same positive nature of the drug can be properly harnessed to provide relief in different cases of this condition.

This study was just one phase of multiple steps required before the use of MDMA can be approved as a prescription treatment.

While the results so far have been promising, FDA approval requires successful successive trials done on a wider range and scale.

It is important to note that the use of MDMA to treat psychological disorders is definitely not a novel new-age treatment.

Before it became popular as a party drug, it was employed by therapists in the late 1970s and early 1980s.

Studies involving MDMA were then hindered by the DEA declaring the drug a schedule I substance.

This means it was declared a drug with no accepted medical use and high chances for abuse despite thelack of convincing medical research to back the declaration.

The renewed research is definitely good news for people suffering from PTSD who have sought out many other unsuccessful treatment options.


Although MDMA has been approved for clinical research, it has carried the risk of harmful effects just like all other drugs.

Fortunately, the effects associated with MDMA are often low profile and temporary. Most commonly, this drug increases the heart rate and body temperature.

It can also cause immune system changes, but just for a short period.

These are the observed side effects of pure MDMA. Ecstasy or molly sometimes contains other potentially dangerous substances that may warrant non-related adverse effects.

As such, non-clinical and unsupervised use of the drug is still inadvisable.

Researchers and therapists are hopeful that they will success in following studies, MDMA may be available as an option for PTSD patients in coming years.

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The articles and content found on Dark Web News are for general information purposes only and are not intended to solicit illegal activity or constitute legal advice. Using drugs is harmful to your health and can cause serious problems including death and imprisonment, and any treatment should not be undertaken without medical supervision.


  1. Anonymous

    I would love to be a test subject .

    • Anonymous

      Me too lel

  2. Anonymous

    I know these things, have known them for years, and I’m dumber than a box of rocks. Why those in our government, in positions that they should know these things and pulling down big bucks, don’t know these things is indicative of poor functioning government. And if they are that bad at these things, what else are they doing poorly?

    • Anonymous

      “these things” that you know they know..are they things..i mean are “these things” able to be seen?Or are “these things” the things that other things squeeze inbetween? Im assuming these things are the same things ive seen..maybe..

  3. Anonymous

    this was a good article but it falls flat if the reader is expecting what the title implies. It barely touches on what effects MDMA has on PTSD patients.. It doesnt entirely miss but to live up to the title one would expect to hear some quoted insight from a patient or two and maybe a positive and negative drug response list.. side effects.. study results..maybe some feedback from a tgerapist or two who administered the drug before it became illegal..(i hear a certain famous actress (name rhymes with Begonia Spider) mother was a marriage counselor who practiced MDMA therapy.. but thats just a thing i heard.. and i feel lucky to have heard all about it way back in the late 80s..its rare to be 100% positive that you are ingesting something in its true form..) anyway..good read could have been more in depth or on topic but not terrible.. maybe alter the title.


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